Vacancies
The BDA group has the following positions available. For more information, contact
A.K. Smilde (
)
.
PhD positions, appointment for 4 years
-
A knowledge base of polyphenol degradation routes in humans using concept maps will be build.
Based on this, systems biology models will be made. Finally, validating the knowledge base using
systems biology model results will be explored.
-
Protein-protein interaction networks of the protein makeup of synapses in the brain will be build. From
these networks, methods to predict new protein complexes have to be developed.
-
Grey modeling methodology will be developed that combines data driven models and prior information
to build systems biology models. The main research questions are how to incorporate various types of prior
knowledge in these models and how to validate the grey models.
Scientific programmer position
-
As part of the systems bioinformatics project the scientific programmer will work on the
BioExpert project. The overall aim of the BioExpert project
is to develop a framework to represent, integrate and present (curated) knowledge of specific
biological systems and to use this information in subsequent modelling applications. The overall
framework is based on state-of-the-art approaches for Information Management (e.g., RDF/OWL) and
novel approaches for information (re)presentation (i.e., concept map network). The BioExpert
knowledge base stores conceptual models that provide a comprehensive, accurate, and up-to-date
description of selected biological systems to serve as input for mathematical modeling.